Create a short memoir about an event in your life. Only, instead of using just words, add illustrations to tell the story. In other words, make it a graphic novel memoir.
Write about two characters who have reunited after many years apart. How have they changed? Do they still interact with each other the same way?
Write a story within a story. Maybe one of your characters reads a book, watches a movie or sees a play that informs the overarching plot.